Safety and Feasibility of Autologous Myoblast Transplantation in Patients With Ischemic Cardiomyopathy
نویسندگان
چکیده
Nabil Dib, MD, MSc; Robert E. Michler, MD; Francis D. Pagani, MD, PhD; Susan Wright, BS, RN; Dean J. Kereiakes, MD; Rose Lengerich, RN; Philip Binkley, MD; Diane Buchele, BSN, CNOR; Inder Anand, MD, DPhil; Cory Swingen, MS; Marcelo F. Di Carli, MD; James D. Thomas, MD; Wael A. Jaber, MD; Shaun R. Opie, PhD; Ann Campbell, BSN, RN; Patrick McCarthy, MD; Michael Yeager, RN; Vasken Dilsizian, MD; Bartley P. Griffith, MD; Ronald Korn, MD, PhD; Steven K. Kreuger, MD; Marwan Ghazoul, MD; W. Robb MacLellan, MD; Gregg Fonarow, MD; Howard J. Eisen, MD; Jonathan Dinsmore, PhD; Edward Diethrich, MD
منابع مشابه
Safety and feasibility of autologous myoblast transplantation in patients with ischemic cardiomyopathy: four-year follow-up.
BACKGROUND Successful autologous skeletal myoblast transplantation into infarcted myocardium in a variety of animal models has demonstrated improvement in cardiac function. We evaluated the safety and feasibility of transplanting autologous myoblasts into infarcted myocardium of patients undergoing concurrent coronary artery bypass grafting (CABG) or left ventricular assist device (LVAD) implan...
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متن کاملThe Myoblast Autologous Grafting in Ischemic Cardiomyopathy (MAGIC) trial: first randomized placebo-controlled study of myoblast transplantation.
BACKGROUND Phase I clinical studies have demonstrated the feasibility of implanting autologous skeletal myoblasts in postinfarction scars. However, they have failed to determine whether this procedure was functionally effective and arrhythmogenic. METHODS AND RESULTS This multicenter, randomized, placebo-controlled, double-blind study included patients with left ventricular (LV) dysfunction (...
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تاریخ انتشار 2005